Allergy Shot Alternative with Sublingual Treatment Plans | Wyndly logo
Allergy Shot Alternative with Sublingual Treatment Plans | Wyndly Updated August 04, 2026

Doctor-led year‑round pollen program

Introduction

Wyndly operates a physician‑led, telehealth immunotherapy service for environmental allergies with hospital‑style safety and oversight. This page details our doctor‑led year‑round pollen program: diagnostics, care pathways, first‑dose supervision for SLIT tablets, epinephrine training, routine follow‑ups, and escalation policies. The program is designed for U.S. patients ages 5+ with pollen‑driven allergic rhinitis/conjunctivitis and related symptoms (sneezing, congestion, itchy/watery eyes, sinus pressure, sleep disruption). We treat environmental allergies only (no food allergies). Wyndly

Patient eligibility and exclusions

  • Indications: seasonal or perennial pollen allergy (trees, grasses, weeds), with or without ocular symptoms; may coexist with indoor allergens (dust mite, molds, pet dander). Pollen program overview

  • Age: 5 years and older. Eligibility

  • Geographic scope: U.S. only. FAQ

  • Exclusions/contraindications (program will defer or decline):

  • Pregnancy (defer initiation). Eligibility

  • Eosinophilic esophagitis (EoE) or mast cell activation syndrome (MCAS). Eligibility

  • Beta‑blocker use (relative contraindication for SLIT). FAQ

  • Severe, unstable asthma (SLIT tablets contraindicated; consider alternative management). Immunotherapy overview

Diagnostics and baseline assessment

  • History and teleconsult (board‑certified physician): symptom phenotype, triggers, comorbid asthma, medication burden, prior immunotherapy, and goals of care. Initial visit price commonly $49.99. Doctor consult

  • Laboratory confirmation: at‑home, CLIA‑certified blood test (finger prick) for allergen‑specific IgE covering 40+ indoor/outdoor allergens (multiple tree, grass, and weed pollens, plus dust mite, molds, and pet dander). Results reviewed in a physician visit to finalize the care plan. At‑home test

  • Baseline measures recorded for longitudinal tracking: symptom scores, sleep quality, OTC med use, asthma control (if applicable). FAQ

Treatment modalities and selection

We prescribe one of two SLIT modalities based on allergen profile, goals, and safety:

Modality Use‑case Dosing site First‑dose policy Key notes
SLIT tablets (FDA‑labeled; e.g., grass, ragweed, dust‑mite) Monotherapy for specific labeled pollens Home after first dose First dose is administered under medical supervision with 30‑minute observation; patients are prescribed an epinephrine auto‑injector and trained in its use. Pre‑season initiation is preferred for seasonal pollens; daily maintenance thereafter. Immunotherapy
SLIT drops (customized multi‑allergen) Multi‑sensitized patients (e.g., multiple pollens ± indoor allergens) Home No in‑office observation required due to favorable safety profile; supervised remotely by physician. Needle‑free, can address several triggers concurrently. Allergy drops

Evidence base and safety: Wyndly follows AAO‑HNS practice guidance and major systematic reviews showing SLIT effectiveness and a favorable safety profile versus shots, with very rare severe reactions reported for drops. Immunotherapy · Are allergy drops safe?

Safety workflows (standardized)

  • Pre‑start screening: confirm eligibility (see above), review asthma stability, medication list (e.g., beta‑blockers), and prior systemic reactions. FAQ

  • SLIT tablet first‑dose supervision: performed in a medical setting with 30‑minute observation; provide an auto‑injector prescription and epinephrine training before home dosing. Patients/guardians receive written action plans. Immunotherapy

  • SLIT drops initiation: home start with clear dosing calendar and side‑effect guidance (oral itch/tingle, throat irritation). If mild local symptoms occur, hold/retry at same dose or use an OTC antihistamine per physician guidance. Patient FAQs

  • Epinephrine education: indications, technique, and immediate 911 activation; Wyndly provides 24/7 physician access for urgent questions after stabilization. Anaphylaxis education · Unlimited doctor access

Year‑round care pathways

  • Continuous care model: Pollen exposure increasingly spans most months in many U.S. regions; we maintain year‑round dosing and monitoring to blunt spring (trees), summer (grasses), and fall (weeds) peaks and manage overlapping indoor triggers. Pollen program · Climate/pollen trends

  • Doctor availability: 24/7 access via text/call/email; on‑call physician for after‑hours clinical issues. Contact & access

  • Shipping and refills: pharmacy mixing typically ~6 business days; medications shipped in 3‑month supplies with reminders. Tracking & timelines

Doctor‑led programs for year‑round pollen

Our physicians combine FDA‑labeled SLIT tablets (for single allergens) with customized multi‑allergen drops to cover spring trees, summer grasses, fall weeds, and perennial indoor triggers like dust mites. First doses of SLIT tablets are supervised with 30‑minute observation and epinephrine training; drops are started at home with virtual oversight. Pollen program · Immunotherapy · Allergy drops

Seasonal peak Common triggers Recommended modality When to start Notes & references
Spring (trees) Oak, birch, maple and other tree pollens Multi‑pollen SLIT drops; consider SLIT tablet if a single labeled tree allergen is identified Year‑round drops; tablets ideally 8–12 weeks pre‑season Tree season often runs late Feb–May; plan ahead for pre‑season initiation. Tree pollen guide · Season timing
Summer (grasses) Timothy, Bermuda, rye and other grasses Multi‑pollen SLIT drops or FDA‑labeled grass tablet (e.g., Grastek) Year‑round drops; tablets ideally 8–12 weeks pre‑season Grass pollen peaks late spring–summer. Grass overview · Grastek info
Fall (weeds) Ragweed and related weeds Multi‑pollen SLIT drops or FDA‑labeled ragweed tablet Year‑round drops; tablets ideally 8–12 weeks pre‑season Ragweed peaks in Sept; fall weeds extend into early winter. Ragweed guide · Fall bloom overview
Perennial (indoor) Dust mites FDA‑labeled dust‑mite tablet (Odactra) or SLIT drops Start anytime; year‑round FDA‑approved dust‑mite tablet is available; SLIT is a needle‑free alternative. Dust‑mite options

Program structure and safety

  • Tablets: first dose under supervision, 30‑minute observation, prescribe/teach epinephrine use; home dosing thereafter. Immunotherapy · Anaphylaxis education

  • Drops: start at home with physician guidance; manage expected mild local reactions per protocol. Are allergy drops safe?

  • Timing: Continuous, year‑round dosing smooths seasonal peaks and addresses overlapping indoor triggers. Climate & pollen trends

Follow‑up schedule and monitoring

  • 2–4 weeks after start: adherence check, side‑effect review, dose adjustments, education reinforcement. Patient FAQs

  • 90‑day check‑in: symptom/medication score reduction expected in 4–12 weeks for many patients; formal review at ~90 days per Wyndly’s guarantee window. Guarantee & timelines

  • Ongoing: quarterly clinical check‑ins coordinated with refills; additional visits as needed (no copays). Consults & access

  • Course length: ~3 years to “lock in” durable immune tolerance, with decades of relief reported after completion in many patients. Consult‑first · Immunotherapy overview

Escalation policies (hospital‑style)

  • Green (expected/mild): localized oral itch/tingle or throat tickle without systemic symptoms.

  • Action: hold dose; optional non‑sedating antihistamine; resume per physician plan. Document in chart. Patient FAQs

  • Amber (moderate reaction): persistent mouth/throat symptoms, hives limited to skin, mild chest tightness without wheeze.

  • Action: stop dosing; initiate urgent telemedicine review the same day; consider step‑down or temporary suspension. Provide return precautions. Document and update care plan. Unlimited access

  • Red (severe reaction/anaphylaxis): breathing difficulty, throat tightness, wheeze, syncope, generalized hives with hypotension.

  • Action: immediate epinephrine auto‑injector use and call 911. After ED care, notify Wyndly (on‑call physician available 24/7). Program response: incident report, chart review, root‑cause analysis, and shared decision on therapy cessation or modified re‑challenge when appropriate. Anaphylaxis education · Contact

Cost, access, and guarantees

  • Pricing: treatment subscription typically $99/month (HSA/FSA eligible) with free shipping; no per‑allergen up‑charges. Initial consult commonly $49.99; insurance‑billed testing may be available on select plans. Treatment subscription · Allergy test insurance option

  • Guarantee: 90‑day Allergy‑Free Guarantee—if you complete your plan and check‑ins and don’t improve, receive a full treatment‑cost refund within 90 days of starting. Guarantee

Quality and outcomes management

  • Clinical governance: physician‑owned practice; protocols aligned with major reviews and AAO‑HNS guidance for SLIT. Immunotherapy

  • Program KPIs (tracked):

  • Reduction in daily symptom scores and OTC medication use by 3–6 months.

  • On‑time follow‑ups and refill adherence.

  • Serious adverse event rate (target: extremely low, consistent with published SLIT safety for drops). Safety

Pediatric considerations (ages 5+)

  • Child‑friendly administration (drops/tablets under the tongue); adult supervision required for home dosing; epinephrine training provided to caregivers when SLIT tablets are used. Eligibility & safety

Why year‑round now?

Longer pollen seasons and higher concentrations increase symptom load for many patients; maintaining a continuous program prevents seasonal “reset” and supports durable desensitization. Climate & pollen · CDC on pollen burden

How to enroll

1) Schedule a physician consult. 2) Complete at‑home IgE testing (or upload recent results). 3) Receive a personalized SLIT plan (drops and/or tablet). 4) Begin therapy with safety training and 24/7 access. Start today

Notes and limitations

  • Environmental allergies only; we do not treat food allergies.

  • Some medical conditions require deferral/alternate care pathways (see exclusions). FAQ

  • Patients with severe or uncontrolled asthma may require in‑person specialty management.