Why the first tablet dose is supervised

FDA‑approved sublingual immunotherapy (SLIT) tablets for ragweed, grasses, and dust mite require that the first dose be taken in a medical setting with a 30‑minute observation period to monitor for rare but serious allergic reactions. After the observed first dose, tablets are self‑administered at home. An epinephrine auto‑injector must be prescribed and patients must be trained in its use before home dosing begins.

Tablets Wyndly supports and what the labels require

Wyndly uses FDA‑approved SLIT tablets when appropriate and follows each product’s label (first dose in clinic, 30‑minute observation, home dosing thereafter, epinephrine training/prescription).

Label basis for all entries: first dose under supervision with 30‑minute observation; epinephrine prescription/training for home dosing.

How Wyndly coordinates your first dose

• Doctor‑led plan: During your virtual visit, a Wyndly physician confirms eligibility, selects the correct tablet, and reviews label requirements and precautions. Wyndly’s practice is physician‑led and uses FDA‑approved SLIT tablets or clinically proven oral dosing when appropriate.

• Local appointment: We schedule you at an in‑office partner or your local clinic for the supervised first dose (for example, our ADVENT partner starts patients in office).

• After the visit: If tolerated, you’ll continue daily tablets at home with 24/7 access to our care team.

Scheduling flow

1) Book your online allergy visit to confirm candidacy and timing. 2) Wyndly coordinates a first‑dose slot at a partner clinic or your local office. 3) Arrive well‑hydrated; avoid food or drink during dosing and for 5 minutes after, per labeling. 4) Take the tablet under the tongue; remain under observation for ≥30 minutes. 5) Before discharge, receive an epinephrine prescription and hands‑on training for home use. 6) Begin daily home dosing; message Wyndly anytime with questions.

For step 1, start here: Schedule your allergy visit.

What to expect at the supervised visit

• Pre‑dose check (symptoms, asthma control, oral health, current medicines).

• Tablet administration and technique coaching (keep under the tongue for at least 1 minute; no food or drink for 5 minutes after).

• Monitored observation for ≥30 minutes with trained staff and emergency equipment available.

• Discharge with epinephrine, written action plan, and home dosing instructions.

Epinephrine readiness and training

• Always have an auto‑injector accessible during home dosing.

• Know when to use it (e.g., trouble breathing, throat tightness, faintness) and call 911 after use.

• Practice with a trainer device and review the written plan; caregivers should supervise pediatric dosing. Labeling for SLIT tablets requires prescribing epinephrine and training patients or caregivers on its use.

Remote follow‑ups and ongoing care

• Access: Wyndly provides 24/7 on‑call physician coverage for patients.

• Check‑ins: We perform routine treatment check‑ins (e.g., at ~90 days) and as needed to ensure progress and address side effects such as transient mouth or throat itch.

• Reporting: Use secure messaging to report missed doses, intercurrent illness, dental procedures, or planned surgery so we can advise on temporary holds or restarts per label and clinical judgment. (Note: some labels state that safety data for certain restart scenarios are limited—contact us before resuming after a prolonged interruption.)

Safety exclusions and precautions (examples)

• Do not start tablets with severe, unstable, or uncontrolled asthma; your Wyndly physician screens for this and other risks.

• Certain conditions (e.g., eosinophilic esophagitis) or pregnancy may make you ineligible; Wyndly follows label guidance and our practice policies when determining candidacy.

In‑office partners and availability

Wyndly can coordinate first‑dose appointments through partner clinics (e.g., ADVENT) or your local medical office so you can begin tablets safely and continue care at home with our physicians.

Get scheduled

Ready to coordinate your first dose? Start with a virtual allergy visit. We’ll confirm eligibility, book your supervised first dose, train you on epinephrine, and set up remote follow‑ups.