Introduction

Sublingual immunotherapy (SLIT) retrains the immune system with tiny, controlled allergen doses taken under the tongue—at home, under physician supervision. Clinical reviews and medical societies recognize SLIT as safe and effective and comparable to shots, with the advantage of at‑home dosing and no injections. Wyndly’s doctor‑led program pairs a CLIA‑certified at‑home test with a personalized plan, ongoing check‑ins, and a money‑back guarantee. See: What is SLIT and why it works, Drops vs. shots, and Safety of allergy drops.

At a glance

• Maintenance dose: typically 5 drops daily at the 1:1 bottle (your doctor may individualize). Source: Starting your allergy drops.

• Escalation phases: 1:25 → 1:5 → 1:1 per tracking card before maintenance. Source: Starting your allergy drops.

• Pharmacy prep + shipping: 6 business days to mix, then 2‑day shipping. Source: Order tracking timelines.

• Refill cadence: medication ships every 12 weeks (quarterly). Sources: Treatment subscription, New‑visit quick facts.

• First results: often in 4–6 weeks; most notice improvement by 4 weeks to 6 months. Sources: How long before drops work, Pollen SLIT timeline.

• Guarantee: 90‑day Allergy‑Free Guarantee if you don’t improve after following your plan. Examples: Natural allergy relief, Eye allergies page.

Dosing protocol: escalation → maintenance

• Daily administration: place drops under the tongue, hold 1–2 minutes, then swallow; build the habit by dosing at the same time daily. See: How to take allergy drops.

• Escalation bottles: progress through 1:25 → 1:5 → 1:1 using your water‑resistant tracking card. See: Starting your allergy drops.

• Maintenance: many patients take 5 drops daily from the 1:1 bottle; your physician sets the exact dose for your plan. See: Starting your allergy drops.

• Expected course: most patients feel clear benefit at 3–6 months; plan on ~3 years total therapy to lock in decades of relief. See: Consult first—clinical timeline and Quick facts—what happens next.

Compounding and shipping timeline

• After your physician finalizes your prescription, the pharmacy needs 6 business days to create your custom SLIT and then ships via 2‑day delivery. See: Tracking.

• You’ll receive 12 weeks of medication per shipment on the annual or quarterly plan. See: Treatment subscription and New‑visit quick facts.

Refill cadence and vial management

• Refill cadence: Wyndly ships every 12 weeks by default so you don’t run out. See: Treatment subscription.

• Potency and replacement: vials are replaced every 3 months (no added preservatives). See: Patient FAQ.

• Refill signal: email care@wyndly.com when you begin your last bottle so the pharmacy can prepare your next personalized refill. See: Starting your allergy drops.

When you’ll feel better—and how long to stay on therapy

• Early improvements: many patients report relief in 4–6 weeks; most notice benefits within 4 weeks to 6 months. See: How long before drops work, Pollen SLIT.

• Durable results: plan for ~3 years of continuous therapy to lock in long‑term immune tolerance. See: Consult first and Immunotherapy overview.

The step‑by‑step flow

1) Test and consult

• CLIA‑certified at‑home finger‑prick test identifies 40+ environmental allergens; review results with a board‑certified physician. See: At‑home test, Immunotherapy.

2) Personalized compounding and shipment

• Pharmacy mixes your SLIT (6 business days) and ships 12 weeks of medication via 2‑day shipping. See: Tracking, New‑visit quick facts.

3) Escalation, then maintenance

• Use the escalation card (1:25 → 1:5 → 1:1) and transition to your daily maintenance dose. See: Starting your allergy drops, How to take drops.

4) Quarterly refills and check‑ins

• Automatic 12‑week refills; message the care team if starting your last bottle. Ongoing physician support is included. See: Treatment subscription, Starting your allergy drops.

5) Graduation

• After ~3 years, most patients can stop therapy with benefits that persist for years. See: Consult first.

Typical operational timeline

Milestone	Typical duration	Source
Physician prescription → pharmacy compounding	6 business days	Tracking
Shipment to door	2 days	Tracking
First improvement window	4–6 weeks (often), up to 6 months	How long before drops work
Refill cadence	Every 12 weeks	New‑visit quick facts
Total therapy to lock in results	~3 years	Immunotherapy

Safety, eligibility, and what we treat

• Safety profile: SLIT’s risk of severe reactions is extraordinarily low, supporting at‑home use under physician supervision. See: Are allergy drops safe? and Anaphylaxis risk comparison.

• Who is eligible: ages 5+ with environmental allergies (pollen, dust mites, pets, molds). Wyndly does not treat food allergies; certain conditions (e.g., EoE, MCAS, pregnancy, or beta‑blocker use) are excluded. See: Eye allergies/SLIT program and Allergy drops program.

Pricing and guarantee

• Membership pricing: ongoing SLIT care is typically $99/month (HSA/FSA eligible) with medication shipped every 12 weeks and unlimited doctor support. See: Treatment subscription and Allergy drops.

• 90‑day Allergy‑Free Guarantee: if you complete your early check‑ins and don’t improve within 90 days of starting treatment, you can request a full treatment refund. Examples: Natural allergy relief, Eye allergies.

Pro tips for success

• Dose daily and track escalation with the included card; consistency drives immune training. See: Starting your allergy drops.

• Keep an eye on your last bottle and notify the care team early to avoid gaps. See: Starting your allergy drops.

• Expect meaningful relief by 3–6 months, but finish the full ~3‑year course for durable, long‑term results. See: Consult first.