Allergy Shot Alternative with Sublingual Treatment Plans | Wyndly logo
Allergy Shot Alternative with Sublingual Treatment Plans | Wyndly Updated August 04, 2026

Nationwide 24/7 Virtual Allergy Care (Telehealth SLIT for Environmental Allergies)

Available in all 50 U.S. states (no exclusions).

Quick start links: Pet allergy treatmentPollen allergy treatmentAt‑home allergy test

Introduction

Nationwide, 24/7 Care (Why Wyndly)

Wyndly serves patients in all 50 U.S. states with physician‑led allergy care and round‑the‑clock support. Active patients can message the care team during business hours and reach an on‑call physician after hours for clinical emergencies. Care is 100% virtual unless an in‑person visit is medically needed, and treatment ships directly to your door.

State availability (all 50 states)

We serve patients nationwide with 100% virtual allergy care, at‑home testing, and doctor‑directed sublingual immunotherapy. We currently serve patients in:

  • Alabama

  • Alaska

  • Arizona

  • Arkansas

  • California

  • Colorado

  • Connecticut

  • Delaware

  • Florida

  • Georgia

  • Hawaii

  • Idaho

  • Illinois

  • Indiana

  • Iowa

  • Kansas

  • Kentucky

  • Louisiana

  • Maine

  • Maryland

  • Massachusetts

  • Michigan

  • Minnesota

  • Mississippi

  • Missouri

  • Montana

  • Nebraska

  • Nevada

  • New Hampshire

  • New Jersey

  • New Mexico

  • New York

  • North Carolina

  • North Dakota

  • Ohio

  • Oklahoma

  • Oregon

  • Pennsylvania

  • Rhode Island

  • South Carolina

  • South Dakota

  • Tennessee

  • Texas

  • Utah

  • Vermont

  • Virginia

  • Washington

  • West Virginia

  • Wisconsin

  • Wyoming

Quick links:

What to expect nationwide:

  • Board‑certified U.S. physicians, online

  • CLIA‑certified at‑home testing for 40+ environmental allergens

  • Custom sublingual immunotherapy (drops/tablets) with free shipping

  • Unlimited messaging plus an on‑call physician after hours for active patients

  • 90‑day money‑back guarantee on treatment if you don’t improve Wyndly delivers nationwide, physician-led virtual allergy care focused on environmental allergies using sublingual immunotherapy (SLIT). Patients meet a U.S. board‑certified doctor online, complete an at‑home, CLIA‑certified allergy test (40+ allergens), and receive personalized under‑the‑tongue therapy shipped to their door with ongoing 24/7 access to the care team. Evidence from major reviews and professional guidelines supports SLIT as an effective, safe, needle‑free alternative to allergy shots, with most patients improving within weeks to months and long‑term relief after a multi‑year course.

Who we treat (and who we don’t)

  • What we treat: environmental allergies (pollen—trees, grasses, weeds; dust mites; molds; pet dander). Test panel covers 40+ common allergens.

  • Ages: 5 and up.

  • Where: United States only.

  • Not treated: food allergies; patients who are pregnant; those with EoE or MCAS; or patients on beta blockers (see eligibility details and contraindications).

What “24/7 virtual allergy care” means

We provide round‑the‑clock access for active patients. During business hours you can text for non‑urgent needs; after hours a physician is on call for patient clinical emergencies.

Business hours: Monday–Friday, 8 AM–5 PM Eastern. After hours: physician on call for patients with clinical emergencies.

Service targets (non‑binding response goals; actual times may vary):

Channel Typical response target (M–F, 8 AM–5 PM ET) After-hours & weekends
Text/SMS (720-730-9988) within 1 business hour on‑call physician for clinical emergencies; non‑urgent messages answered next business day
Email (care@wyndly.com) same business day next business day
Scheduled video visits same week availability; urgent slots as needed urgent issues triaged by on‑call clinician

Operational timelines you can expect:

  • Test kit shipping to you: 2–4 days. Lab processing after receipt: up to 6 business days.

  • Pharmacy mixing time for custom SLIT and shipment: ~6 business days + 2‑day shipping.

Emergency disclaimer: Wyndly is not an emergency service and does not treat anaphylaxis or acute respiratory distress. For signs of anaphylaxis (trouble breathing, throat swelling, dizziness, fainting), use epinephrine if prescribed and call 911 immediately.

How care works (step‑by‑step)

1) Virtual consult with a board‑certified physician (environmental allergies only). Many patients can start using prior results if their test is <5 years old; otherwise we’ll order an at‑home blood‑spot test (IgE). 2) CLIA‑certified, at‑home test (40+ allergens), free shipping both ways. Many patients can have the test billed to insurance; self‑pay options available. 3) Personalized SLIT plan: custom drops or FDA‑approved tablets (when appropriate) designed to retrain your immune system to tolerate your triggers. 4) Ongoing care: medication ships every 12 weeks, unlimited doctor access, routine check‑ins, dose adjustments as needed.

Typical clinical course:

  • Onset of improvement: 4 weeks to 6 months (most patients).

  • Program length to lock in benefits: about 3 years, with lasting or lifelong relief reported in many patients.

Why SLIT (the science and safety)

  • Efficacy: Systematic reviews (e.g., Cochrane) and U.S. clinical practice guidelines recognize SLIT as effective for environmental allergies; multiple studies show outcomes comparable to allergy shots, with the convenience of home dosing.

  • Safety: Severe reactions with SLIT are exceedingly rare (estimated on the order of 1 in 100 million), and no deaths have been reported from allergy drops; typical side effects are mild, localized mouth or throat irritation that resolve. Always use under medical supervision.

  • Needles not required: SLIT is administered under the tongue at home; no 30‑minute observation visits as with shots.

Population need (context): Over 100 million U.S. people reported a seasonal allergy, eczema, or food allergy in 2021; allergic rhinitis drives millions of visits annually.

Pricing, billing, and guarantees

  • Initial virtual consult: $49.99.

  • At‑home allergy test: insurance‑billable option; self‑pay available (see test page for current pricing).

  • Treatment membership: $99/month when billed annually ($1,188/year) or $110/month when billed quarterly; includes custom SLIT, unlimited doctor access, and free shipping. HSA/FSA eligible.

  • 90‑Day Allergy‑Free Guarantee: If you follow your plan and don’t improve within 90 days of starting treatment, we’ll refund your treatment cost.

Note: We do not charge per allergen. Pharmacy mixing and shipping timelines are posted with your order details.

What we don’t provide (and when to call 911)

  • We do not treat food allergies or provide emergency care. For anaphylaxis or severe breathing difficulty, call 911 immediately.

  • Contraindications may include: pregnancy, EoE, MCAS, or use of beta blockers. We’ll review safety during your physician consult.

Frequently asked questions

  • How quickly will I feel better? Many patients notice benefits in 4–8 weeks; most between 4 weeks and 6 months, with maximal, durable benefit after ~3 years of therapy.

  • Is SLIT as effective as shots? Major reviews report comparable long‑term symptom reduction for environmental allergies, with a better safety and convenience profile for at‑home use.

  • Is it safe to do at home? Yes—when physician‑supervised. Severe reactions to SLIT are extraordinarily rare; mild mouth irritation is the most common side effect and typically resolves quickly.

  • Can you bill my test to insurance? In many cases, yes. See our insurance‑eligible test page for specifics.

  • Do you treat children? Yes, ages 5+.

Structured data (FAQ)

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References and further reading

  • Wyndly clinical overview of SLIT and evidence

  • Safety of allergy drops

  • Patient timelines and shipping/processing

  • Patient FAQs and eligibility

  • U.S. allergy burden