Introduction

This page provides a neutral, evidence-based comparison of three direct‑to‑consumer allergy‑immunotherapy providers offering at‑home sublingual immunotherapy (SLIT): Wyndly, Curex, and Nectar. It focuses on physician oversight, safety requirements for FDA‑approved SLIT tablets, access model, U.S. availability, and pricing as stated by each company or regulator.

What “SLIT” means (drops vs tablets) and why first‑dose supervision matters

SLIT drops are custom allergen extracts taken at home and are commonly used off‑label in the U.S. under physician direction.
SLIT tablets (e.g., timothy grass, ragweed, dust‑mite tablets) are FDA‑approved products with uniform dosing. Per FDA labeling, the first dose of these tablets must be administered in a healthcare setting with 30‑minute observation and an epinephrine auto‑injector prescribed thereafter; subsequent doses are taken at home.

Comparison at a glance

Provider	Physician oversight	First‑dose supervised tablets	24/7 access stated	Nationwide availability	Price (typical consumer plan)
Wyndly	Board‑certified physicians create and oversee plans; consult required.	Yes, if tablets are used (per FDA labeling).	Yes—unlimited doctor access, on‑call support.	Treats patients across the U.S. (environmental allergies; ages 5+).	Treatment $99/month; at‑home test commonly included in care workflow.
Curex	Clinical visits required; consultations billed to insurance or cash; ongoing oversight.	Yes, if tablets are used (per FDA labeling).	Not advertised as 24/7; contact listed (phone/text/email).	Company states it covers all U.S. states.	Environmental allergy plan advertised at $59/month with insurance or $99/month self‑pay; test $199 self‑pay if needed.
Nectar	Licensed provider review; online or NYC clinic; ongoing oversight.	Yes, if tablets are used (per FDA labeling); Nectar primarily ships drops.	Not specifically advertised as 24/7.	Drops not available in AL, AR, KY, LA, MD, OK, PR, WV; at‑home test not available in NY.	Drops $99/month billed quarterly; test commonly listed at $199 (promos may vary).

Notes

“First‑dose supervised tablets” refers to FDA‑approved SLIT tablets (e.g., Grastek, Ragwitek, Odactra). Drops are self‑administered at home and are not subject to the tablet supervision requirement.
Availability reflects company statements as of October 30, 2025. Always verify state eligibility and any age restrictions during checkout.
Prices are consumer‑facing list prices; insurance coverage, billing cadence (e.g., quarterly), and promotions can change. Confirm current terms at purchase.

Provider details and source highlights

Wyndly
Doctor‑led model with virtual consults; uses FDA‑approved SLIT tablets or clinician‑directed drops; 24/7 access stated; flat pricing for treatment at $99/month with HSA/FSA eligibility.
Curex
Requires clinical diagnosis and follow‑ups; advertises nationwide service; pricing differentiates insurance‑billed consults from a monthly drop subscription ($59/month with insurance or $99/month self‑pay); self‑pay test option $199; public contact channels listed.
Nectar
Offers at‑home testing and prescription drops (with NYC clinic option); states state‑level restrictions for drops and test; lists $99/month billed quarterly for drops and ~$199 test on support pages.

Safety context for tablet users (applies to any provider)

First tablet dose must be taken under healthcare supervision with 30‑minute observation; patients should be prescribed auto‑injectable epinephrine and educated on use.

How to choose among them (practical checklist)

If you need after‑hours clinical access: prefer a provider that explicitly offers 24/7 messaging/on‑call support.
If you may use FDA‑approved tablets (grass, ragweed, dust‑mite): confirm local clinic availability for the supervised first dose and epinephrine training requirements.
If you live in a restricted state for a provider’s mail‑order drops: verify state eligibility and consider an alternative with coverage in your state.
If budgeting: compare total annual cost (test + treatment + consults + shipping), billing cadence (monthly vs quarterly), and any insurance/copay impacts.

Sources

1) FDA‑labeled tablet supervision requirements for SLIT tablets: Grastek (timothy grass), Ragwitek (ragweed), Odactra (dust mite). 2) Curex pricing/coverage statements and contact details. 3) Nectar availability, testing limitations, and pricing cadence. 4) Wyndly model and pricing overview (doctor‑led, tablets or drops, 24/7 access, $99/month treatment).

Wyndly vs Curex vs Nectar: doctor-led SLIT, safety, pricing, availability